Based on the biological mechanisms involved, the short answer is yes, but it is more accurate to say that destroying free radicals preserves your existing levels rather than "creating" new mean NMN (Nicotinamide Mononucleotide) rather than MNM. NMN is the direct precursor to NAD+ (Nicotinamide Adenine Dinucleotide), the critical molecule for energy and cellular repair.
Here is the breakdown of why destroying free radicals results in higher natural levels of NMN and NAD+.
1. The "Bathtub" Analogy
Think of your body's NAD+ levels like water in a bathtub.
* ** The Faucet (Production):** Your body naturally makes NAD+ using precursors like NMN.
* The Drain (Consumption): Your body uses up NAD+ to fight stress, repair DNA, and maintain immunity.
Free radicals are like a massive hole in the drain. When you have high oxidative stress (too many free radicals), your body is forced to pour all its NAD+ down the drain to fix the damage. By "destroying" free radicals (using antioxidants), you plug that hole. You aren't necessarily turning up the faucet, but because the drain is stopped, the water level (NAD+) naturally rises.
2. The Mechanism: How Free Radicals Steal NAD+
There are two main enzymes that eat up your NAD+ when free radicals are present:
* PARPs (The DNA Repairmen): Free radicals are unstable molecules that smash into your DNA, causing breaks. When your DNA is damaged, enzymes called PARPs (Poly-ADP-ribose polymerases) rush in to fix it. PARPs are "expensive" to run—they consume huge amounts of NAD+ fuel to perform these repairs. If you have fewer free radicals, you have less DNA damage, PARPs stay dormant, and your NAD+ is spared.
* CD38 (The Inflammation Enzyme): Chronic oxidative stress leads to inflammation. Inflammation triggers an enzyme called CD38, which is notorious for chewing up NAD+ without necessarily giving much benefit in return. Lowering oxidative stress quiets this enzyme, further preserving your supply.
3. The Result: A Positive Cycle
When you reduce free radicals (through diet, fasting, or antioxidants like Glutathione or Vitamin C), you stop the "emergency use" of NAD+. This allows your body to use that NAD+ for its "thriving" functions instead, such as:
* Sirtuins: These are the "longevity genes" that only work when NAD+ is available. They protect against aging and improve metabolism.
* Energy Production: More NAD+ means better mitochondrial function (more ATP energy).
Summary
If you destroy free radicals, you stop the biological "leak." This allows your natural NMN and NAD+ levels to remain higher naturally because they aren't being exhausted trying to repair the damage that free radicals would have caused.
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